J William Gaynor Selected Research

Congenital Heart Defects (Congenital Heart Defect)

1/2022	Association of Ongoing Cerebral Oxygen Extraction During Deep Hypothermic Circulatory Arrest With Postoperative Brain Injury.
5/2021	Deep hypothermic circulatory arrest in cyanotic piglets is associated with increased neuronal necrosis.
1/2021	Increased cerebral mitochondrial dysfunction and reactive oxygen species with cardiopulmonary bypass.
1/2021	Standardized Feeding Approach Mitigates Weight Loss in Infants with Congenital Heart Disease.
1/2020	De Novo Damaging Variants, Clinical Phenotypes, and Post-Operative Outcomes in Congenital Heart Disease.
1/2020	Ex Utero Extracorporeal Support as a Model for Fetal Hypoxia and Brain Dysmaturity.
12/2018	Brain Injury During Transition in the Newborn With Congenital Heart Disease: Hazards of the Preoperative Period.
10/2018	Longitudinal Assessment of Outcome From Prenatal Diagnosis Through Fontan Operation for Over 500 Fetuses With Single Ventricle-Type Congenital Heart Disease: The Philadelphia Fetus-to-Fontan Cohort Study.
1/2018	Cumulative Effect of Preoperative Risk Factors on Mortality After Pediatric Heart Transplantation.
1/2018	Autosomal dominant mannose-binding lectin deficiency is associated with worse neurodevelopmental outcomes after cardiac surgery in infants.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

J William Gaynor Research Topics

Disease

34	Congenital Heart Defects (Congenital Heart Defect) 01/2022 - 01/2002
20	Hypoplastic Left Heart Syndrome 08/2021 - 02/2002
8	Seizures (Absence Seizure) 01/2020 - 03/2003
7	Brain Injuries (Brain Injury) 05/2022 - 07/2013
7	Heart Diseases (Heart Disease) 05/2021 - 04/2004
5	Heart Arrest (Cardiac Arrest) 06/2022 - 03/2007
5	Tetralogy of Fallot (Fallot Tetralogy) 01/2021 - 12/2005
5	Hypoxia (Hypoxemia) 01/2020 - 10/2005
5	Birth Weight (Birth Weights) 01/2019 - 07/2002
5	Heart Failure 01/2018 - 09/2007
5	Infections 08/2013 - 10/2002
4	Ventricular Heart Septal Defects (Ventricular Septal Defect) 01/2021 - 12/2010
4	Renal Insufficiency (Renal Failure) 01/2018 - 12/2007
4	Shock 01/2018 - 11/2014
4	Sepsis (Septicemia) 08/2013 - 02/2007
4	Mediastinitis 08/2013 - 04/2005
3	Hypothermia 01/2022 - 01/2018
3	Acute Kidney Injury (Acute Renal Failure) 01/2021 - 07/2015
3	Chromosome Aberrations (Chromosome Abnormalities) 01/2019 - 02/2014
3	Hemorrhage 01/2018 - 01/2003
3	Ischemia 01/2018 - 01/2003
3	Surgical Wound Infection 09/2015 - 04/2007
3	Pleural Effusion (Pleural Effusions) 09/2010 - 02/2002
2	Cyanosis 05/2021 - 08/2003
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 06/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2018
2	Hypotension (Low Blood Pressure) 01/2020 - 03/2007
2	Respiratory Insufficiency (Respiratory Failure) 01/2020 - 09/2015
2	Stroke (Strokes) 01/2018 - 09/2009
2	Ventricular Dysfunction 01/2018 - 02/2008
2	Necrotizing Enterocolitis 11/2017 - 07/2006
2	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2016 - 12/2011
2	Wound Infection (Wound Infections) 09/2015 - 08/2013
2	Protein-Losing Enteropathies (Protein-Losing Enteropathy) 09/2012 - 08/2003
2	Critical Illness (Critically Ill) 09/2007 - 12/2003
2	Low Cardiac Output 03/2007 - 03/2005
2	Sudden Death 03/2007 - 12/2005
1	Clinical Deterioration 01/2022
1	Necrosis 05/2021
1	Angiodysplasia 03/2021
1	Complete atrioventricular septal defect 01/2021
1	Kidney Diseases (Kidney Disease) 01/2021
1	Hematoma 01/2020
1	Premature Birth (Birth, Premature) 01/2019
1	Fetal Hypoxia 12/2018
1	Hearing Loss (Hearing Impairment) 01/2018
1	Cerebrovascular Disorders (Cerebrovascular Occlusion) 07/2015
1	Cardiomyopathies (Cardiomyopathy) 07/2015
1	Traumatic Brain Injuries (Traumatic Brain Injury) 12/2014
1	Brain Ischemia (Cerebral Ischemia) 12/2014
1	Myocarditis (Carditis) 09/2014
1	Aorta-pulmonary artery fistula 09/2014

Drug/Important Bio-Agent (IBA)

7	Oxygen (Dioxygen)IBA 01/2022 - 03/2005
4	Apolipoproteins E (ApoE)IBA 01/2016 - 07/2009
4	ApolipoproteinsIBA 12/2014 - 12/2003
3	Biomarkers (Surrogate Marker)IBA 05/2022 - 03/2003
3	salicylhydroxamic acid (SHAM)IBA 05/2021 - 10/2005
3	CreatinineIBA 01/2021 - 12/2007
3	Proteins (Proteins, Gene)FDA Link 03/2007 - 08/2003
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2021 - 01/2007
2	Phenobarbital (Luminal)FDA Link 01/2020 - 09/2009
2	SteroidsIBA 09/2015 - 02/2012
2	Methylprednisolone FDA LinkGeneric 09/2015 - 02/2012
2	Apolipoprotein E2IBA 01/2008 - 05/2007
1	AngiopoietinsIBA 03/2021
1	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2021
1	omega-Chloroacetophenone (Mace)IBA 01/2021
1	Levetiracetam (Keppra)FDA LinkGeneric 01/2020
1	Adrenergic Receptors (Adrenergic Receptor)IBA 11/2017
1	Furosemide (Lasix)FDA LinkGeneric 10/2017
1	Carbon DioxideIBA 01/2017
1	Anesthetics (Anesthetic Agents)IBA 01/2016
1	Insulin-Like PeptidesIBA 03/2015
1	Cefazolin (Ancef)FDA LinkGeneric 12/2014
1	Methicillin (Metin)FDA Link 12/2014

Therapy/Procedure

21	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2021 - 01/2003
14	Deep Hypothermia Induced Circulatory Arrest 01/2022 - 03/2003
12	Length of Stay 06/2022 - 02/2002
12	Extracorporeal Membrane Oxygenation 01/2021 - 07/2002
10	Fontan Procedure (Fontan Operation) 08/2021 - 02/2002
9	Norwood Procedures 01/2021 - 07/2002
6	Artificial Respiration (Mechanical Ventilation) 01/2019 - 04/2004
6	Sternotomy 01/2018 - 04/2005
5	Critical Care (Surgical Intensive Care) 01/2022 - 03/2007
5	Therapeutics 01/2020 - 02/2005
4	Blalock-Taussig Procedure 03/2016 - 08/2007
3	Arterial Switch Operation 01/2021 - 01/2016
3	Heart Transplantation (Grafting, Heart) 01/2017 - 05/2008
3	Heart-Assist Devices 07/2015 - 07/2002
2	Thoracotomy 05/2021 - 02/2008
2	Cardiopulmonary Resuscitation (CPR) 01/2018 - 11/2017
2	Catheters 09/2017 - 09/2010
2	Tracheostomy 09/2015 - 11/2014
2	Cardiac Procedures Anesthesia 12/2008 - 03/2007
2	Hemodilution 03/2007 - 01/2003
1	Mechanical Ventilators (Ventilator) 01/2020
1	Preoperative Period 12/2018
1	Hearing Aids (Hearing Aid) 01/2018
1	Resuscitation 01/2016
1	Stents 09/2014